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Synaptotagmin I (SYT1) (Middle Region) Peptide

SYT1 Reactivity: Mouse Host: Synthetic BP, WB, IHC
Catalog No. ABIN984679

Quick Overview for Synaptotagmin I (SYT1) (Middle Region) Peptide (ABIN984679)

Target

SYT1 (Synaptotagmin I (SYT1))

Origin

Mouse

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein Region

    Middle Region

    Sequence

    FDRFSKHDII GEFKVPMNTV DFGHVTEEWR DLQSAEKEEQ EKLGDICFSL

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-Syt1 Antibody(ARP59447_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SYT1 (Synaptotagmin I (SYT1))

    Background

    Syt1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2.

    Alias Symbols: AW124717, G630098F17Rik, SytI

    Protein Size: 421

    Molecular Weight

    47 kDa

    Gene ID

    20979

    NCBI Accession

    NM_009306, NP_033332

    UniProt

    P46096
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