Synaptotagmin I (SYT1) (Middle Region) Peptide
Quick Overview for Synaptotagmin I (SYT1) (Middle Region) Peptide (ABIN984679)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- FDRFSKHDII GEFKVPMNTV DFGHVTEEWR DLQSAEKEEQ EKLGDICFSL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Syt1 Antibody(ARP59447_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SYT1 (Synaptotagmin I (SYT1))
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Background
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Syt1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2.
Alias Symbols: AW124717, G630098F17Rik, SytI
Protein Size: 421 -
Molecular Weight
- 47 kDa
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Gene ID
- 20979
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NCBI Accession
- NM_009306, NP_033332
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UniProt
- P46096
Target
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