T-Complex 1 (TCP1) (C-Term) Peptide
TCP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984920
Quick Overview for T-Complex 1 (TCP1) (C-Term) Peptide (ABIN984920)
Target
TCP1 alpha/CCTA (TCP1)
(T-Complex 1 (TCP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- QAGVFEPTIV KVKSLKFATE AAITILRIDD LIKLHPESKD DKHGSYEDAV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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Background
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The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Alias Symbols: CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
Protein Interaction Partner: PDCL,CCT5,CCT7,CDC20,PDCL,TUBA4A,TUBA8,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CTTNBP2,FANCA,GPN1,HDAC1,HDAC3,HSPA8,IGBP1,MOB4,MYC,PPP2CA,PPP2CB,PPP2R2A,PPP2R2B,PPP2R2C,PPP2R2D,PPP2R4,PPP4C,RFWD2,RPAP2,STK24,STK25,STRN,STRN3,TRAF3IP3,UBC,WDR82
Protein Size: 556 -
Molecular Weight
- 61 kDa
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Gene ID
- 6950
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NCBI Accession
- NM_030752, NP_110379
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UniProt
- P17987
Target
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