Transcription Factor A, Mitochondrial (TFAM) Peptide
TFAM
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN984970
Quick Overview for Transcription Factor A, Mitochondrial (TFAM) Peptide (ABIN984970)
Target
TFAM
(Transcription Factor A, Mitochondrial (TFAM))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFAM antibody (Catalog #: ARP36992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Background
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Size: 243 -
Molecular Weight
- 27 kDa
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Gene ID
- 21780
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NCBI Accession
- NM_009360, NP_033386
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UniProt
- P40630
Target
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