Thyroid Hormone Receptor, alpha (THRA) Peptide
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- Target See all THRA products
- THRA (Thyroid Hormone Receptor, alpha (THRA))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-THRA antibody (Catalog #: ARP34780_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- THRA (Thyroid Hormone Receptor, alpha (THRA))
- Background
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The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.
Alias Symbols: AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1, CHNG6
Protein Interaction Partner: GTF2B,BTG1,CDK7,MED21,NCOA1,PCSK2,AKAP13,BTG1,CCND1,CDK7,COPS2,CREB1,CREBBP,CUL1,ESR1,FUS,GTF2B,HDAC2,MED1,MED21,MEF2A,NCOA1,NCOA6,NCOR1,NCOR2,NR2F1,NSD1,OASL,PML,POU2F1,RGN,RXRA,RXRB,RXRG,SLC16A2,SRC,TDG,TRIM24,YWHAH,AKAP13,CCND1,CDK8,COPS2,DAP3,EP300,FUS,HDAC3,HR,Hdac2,ITGB3BP,MED1,MED12,MED16,MED21,MED24,MED6,MEF2A,NCOA6,NCOR1,NR0B2,NRIP1,Nr0b2,Nsd1,PARP1,POU2F1,RXRA,TDG,TRIM24,TRIP11,UBC,YWHAQ,alien
Protein Size: 490 - Molecular Weight
- 55 kDa
- Gene ID
- 7067
- NCBI Accession
- NM_003250, NP_003241
- UniProt
- P10827
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