Thyroid Hormone Receptor, alpha (THRA) Peptide
THRA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985069
Quick Overview for Thyroid Hormone Receptor, alpha (THRA) Peptide (ABIN985069)
Target
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-THRA antibody (Catalog #: ARP34780_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Thyroid Hormone Receptor, alpha (THRA) peptide
THRA Reactivity: Human, Rat, Dog, Mouse, Pig, Cow Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- THRA (Thyroid Hormone Receptor, alpha (THRA))
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Background
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The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.
Alias Symbols: AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1, CHNG6
Protein Interaction Partner: GTF2B,BTG1,CDK7,MED21,NCOA1,PCSK2,AKAP13,BTG1,CCND1,CDK7,COPS2,CREB1,CREBBP,CUL1,ESR1,FUS,GTF2B,HDAC2,MED1,MED21,MEF2A,NCOA1,NCOA6,NCOR1,NCOR2,NR2F1,NSD1,OASL,PML,POU2F1,RGN,RXRA,RXRB,RXRG,SLC16A2,SRC,TDG,TRIM24,YWHAH,AKAP13,CCND1,CDK8,COPS2,DAP3,EP300,FUS,HDAC3,HR,Hdac2,ITGB3BP,MED1,MED12,MED16,MED21,MED24,MED6,MEF2A,NCOA6,NCOR1,NR0B2,NRIP1,Nr0b2,Nsd1,PARP1,POU2F1,RXRA,TDG,TRIM24,TRIP11,UBC,YWHAQ,alien
Protein Size: 490 -
Molecular Weight
- 55 kDa
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Gene ID
- 7067
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NCBI Accession
- NM_003250, NP_003241
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UniProt
- P10827
Target
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