TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) Peptide
Tiparp
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985108
Quick Overview for TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) Peptide (ABIN985108)
Target
Tiparp
(TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TIPARP antibody (Catalog #: ARP33763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
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Background
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TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Alias Symbols: DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14
Protein Interaction Partner: ATM,XRN2
Protein Size: 657 -
Molecular Weight
- 76 kDa
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Gene ID
- 25976
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NCBI Accession
- NM_015508, NP_056323
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UniProt
- Q7Z3E1
Target
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