Toll-Like Receptor 8 (TLR8) (C-Term) Peptide
TLR8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985141
Quick Overview for Toll-Like Receptor 8 (TLR8) (C-Term) Peptide (ABIN985141)
Target
TLR8
(Toll-Like Receptor 8 (TLR8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TLR8 Antibody(ARP59048_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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Background
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Alias Symbols: CD288, MGC119599, MGC119600
Protein Interaction Partner: BTK,MYD88
Protein Size: 1041 -
Molecular Weight
- 120 kDa
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Gene ID
- 51311
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NCBI Accession
- NM_138636, NP_619542
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UniProt
- Q9NR97
Target
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