Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide
TMPRSS3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985282
Quick Overview for Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide (ABIN985282)
Target
TMPRSS3
(Transmembrane Protease, Serine 3 (TMPRSS3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TMPRSS3 Antibody(ARP57683_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
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Background
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This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Alias Symbols: DFNB10, DFNB8, ECHOS1, TADG12
Protein Interaction Partner: EEF1A1,RXRA,EEF1A1,RXRA
Protein Size: 454 -
Molecular Weight
- 50 kDa
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Gene ID
- 64699
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NCBI Accession
- NM_024022, NP_076927
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UniProt
- P57727
Target
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