TNFAIP3 Interacting Protein 1 (TNIP1) (N-Term) Peptide
TNIP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985325
$160.46
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100 μg
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Quick Overview for TNFAIP3 Interacting Protein 1 (TNIP1) (N-Term) Peptide (ABIN985325)
Target
TNIP1
(TNFAIP3 Interacting Protein 1 (TNIP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SPTAPACPSD KPAPVQKPPS SGTSSEFEVV TPEEQNSPES SSHANAMALG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNIP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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Background
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TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
Alias Symbols: ABIN-1, KIAA0113, NAF1, VAN, nip40-1
Protein Size: 636 -
Molecular Weight
- 70 kDa
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Gene ID
- 10318
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NCBI Accession
- NM_006058, NP_006049
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UniProt
- Q15025
Target
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