Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) Peptide
Quick Overview for Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) Peptide (ABIN985472)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIB3 Antibody(ARP57518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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Background
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The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3
Protein Interaction Partner: ATF4,DDIT3,AKT1,AKT2,ATF4,C7orf64,COPS6,DDIT3,EEF1G,GDF9,GIT1,KAT5,RELA,SETDB1,AKT1,ATF4,ATF5,C7orf64,COPS6,CSNK2B,EEF1G,FN1,GDF9,GIT1,GRN,HLA-B,HRSP12,KAT5,LTBP4,MCM3AP,PSMA3,RBM4,RELA,RPSA,SETDB1,SIAH1,TIAF1,UBC
Protein Size: 358 -
Molecular Weight
- 39 kDa
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Gene ID
- 57761
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NCBI Accession
- NM_021158, NP_066981
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UniProt
- Q96RU7
Target
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