Tripartite Motif Containing 27 (TRIM27) Peptide
TRIM27
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985507
Quick Overview for Tripartite Motif Containing 27 (TRIM27) Peptide (ABIN985507)
Target
TRIM27
(Tripartite Motif Containing 27 (TRIM27))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM27 antibody (Catalog #: ARP34701_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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Background
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TRIM27 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
Alias Symbols: RFP, RNF76
Protein Interaction Partner: BEGAIN,CHD4,DNMT1,EID1,EIF3E,EPC1,FBF1,FXYD6,GFI1B,HDAC1,KCTD15,MAGEA11,MCOLN1,PML,PRAM1,RB1,TRIM11,TRIM23,TRIM27,TRIM29,ZBTB16,BEGAIN,DNMT1,EIF3E,FBF1,FXYD6,MAGEA11,MBD2,MBD3,MBD4,MCOLN1,PML,PRAM1,TRIM11,TRIM23,TRIM27,TRIM29,TRIM32,ZBTB16
Protein Size: 358 -
Molecular Weight
- 41 kDa
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Gene ID
- 5987
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NCBI Accession
- NM_030950, NP_112212
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UniProt
- P14373
Target
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