Tripartite Motif Containing 3 (TRIM3) (Middle Region) Peptide
TRIM3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985516
Quick Overview for Tripartite Motif Containing 3 (TRIM3) (Middle Region) Peptide (ABIN985516)
Target
TRIM3
(Tripartite Motif Containing 3 (TRIM3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VKRRVKSPGG PGSHVRQKAV RRPSSMYSTG GKRKDNPIED ELVFRVGSRG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM3 Antibody(ARP57942_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM3 (Tripartite Motif Containing 3 (TRIM3))
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Background
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
Alias Symbols: BERP, FLJ16135, HAC1, RNF22, RNF97
Protein Interaction Partner: ACTN4,MYO5A,TRIM3,UBE2K,ACTN4,TRIM3,UBE2G2,UBE2U
Protein Size: 744 -
Molecular Weight
- 81 kDa
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Gene ID
- 10612
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NCBI Accession
- NM_006458, NP_006449
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UniProt
- O75382
Target
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