Tripartite Motif Containing 32 (TRIM32) Peptide
Quick Overview for Tripartite Motif Containing 32 (TRIM32) Peptide (ABIN985520)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM32 antibody (Catalog #: ARP31692_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM32 (Tripartite Motif Containing 32 (TRIM32))
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Background
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TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Alias Symbols: HT2A, BBS11, TATIP, LGMD2H
Protein Interaction Partner: HIV2gp5,tat,ATXN1,PDE9A,TRIM32,UBQLN1,UBQLN4,ABI2,MID2,PDE9A,PIAS3,SFN,TRIM23,TRIM27,TRIM32,UBC,UBE2N,UBQLN1
Protein Size: 653 -
Molecular Weight
- 72 kDa
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Gene ID
- 22954
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NCBI Accession
- NM_012210, NP_036342
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UniProt
- Q13049
Target
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