Tripartite Motif Containing 63 (TRIM63) (Middle Region) Peptide
TRIM63
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985574
Quick Overview for Tripartite Motif Containing 63 (TRIM63) (Middle Region) Peptide (ABIN985574)
Target
TRIM63
(Tripartite Motif Containing 63 (TRIM63))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- EQLDKSTKLV ETAIQSLDEP GGATFLLTAK QLIKSIVEAS KGCQLGKTEQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM63 Antibody(ARP43365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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Background
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This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Alias Symbols: FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Protein Interaction Partner: MYL2,TRIM63,GMEB1,MYL2,SUMO2,TRIM54,TRIM55,TRIM63,TTN,UBE2I,USP13,AK1,AKR7A2,ALDOA,CKM,Ckm,ENO3,GMEB1,HIBADH,MYL2,MYOT,NEB,NRAP,PDHB,PDK4,PKM2,PYGM,SUMO2,TCAP,TNNC1,TNNI2,TNNT1,TNNT3,TRIM54,TRIM55,TRIM63,TTN,UBE2I,UBE2J1,UBE2U,UQCRC1,USP13
Protein Size: 353 -
Molecular Weight
- 40 kDa
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Gene ID
- 84676
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NCBI Accession
- NM_032588, NP_115977
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UniProt
- Q969Q1
Target
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