Thyroid Stimulating Hormone Receptor (TSHR) (N-Term) Peptide
TSHR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985666
Quick Overview for Thyroid Stimulating Hormone Receptor (TSHR) (N-Term) Peptide (ABIN985666)
Target
TSH receptor (TSHR)
(Thyroid Stimulating Hormone Receptor (TSHR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TSHR antibody (Catalog #: ARP41720_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
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Background
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TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
Alias Symbols: LGR3, MGC75129, hTSHR-I, CHNG1
Protein Interaction Partner: CALR,CANX,HSPA5,SCRIB,TSHR,CALR,CANX,FLNB,FN1,GNA11,GNA12,GNA13,GNAI1,GNAI2,GNAI3,GNAO1,GNAQ,GNAS,HSPA5,JAK1,JAK2,LHCGR,PIK3R1,RABAC1,STAT3,TSHB,TSHR,CALCR,CANX,FLNB,FN1,HSPA5,JAK1,JAK2,STAT3
Protein Size: 764 -
Molecular Weight
- 87 kDa
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Gene ID
- 7253
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NCBI Accession
- NM_000369, NP_000360
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UniProt
- P16473
Target
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