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Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (N-Term) Peptide

TUT1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985760
  • Target See all TUT1 products
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TUT1 antibody (Catalog #: ARP33292_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    Background
    TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6, MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM].

    Alias Symbols: FLJ21850, FLJ22267, FLJ22347, MGC131987, MGC149809, PAPD2, RBM21, TUTase, STARPAP

    Protein Interaction Partner: MEPCE,PRPF4,SART3,USP15,USP4

    Protein Size: 874
    Molecular Weight
    94 kDa
    Gene ID
    64852
    NCBI Accession
    NM_022830, NP_073741
    UniProt
    A8K995
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