Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (Middle Region) Peptide
TUT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985761
Quick Overview for Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1) (Middle Region) Peptide (ABIN985761)
Target
TUT1
(Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TUT1 antibody (Catalog #: ARP39567_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
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Background
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TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6, MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM].
Alias Symbols: FLJ21850, FLJ22267, FLJ22347, MGC131987, MGC149809, PAPD2, RBM21, TUTase, STARPAP
Protein Interaction Partner: MEPCE,PRPF4,SART3,USP15,USP4
Protein Size: 874 -
Molecular Weight
- 94 kDa
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Gene ID
- 64852
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NCBI Accession
- NM_022830, NP_073741
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UniProt
- A8K995
Target
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