Endoplasmic Reticulum Protein 44 (ERP44) (Middle Region) Peptide
Quick Overview for Endoplasmic Reticulum Protein 44 (ERP44) (Middle Region) Peptide (ABIN985777)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TXNDC4 antibody (Catalog #: ARP58726_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
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Background
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TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Alias Symbols: ERP44, KIAA0573, PDIA10, TXNDC4
Protein Interaction Partner: ERO1L,ERO1LB,ITPR1,CD40,ERO1L,ERO1LB,UIMC1,USP32,USP46
Protein Size: 406 -
Molecular Weight
- 45 kDa
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Gene ID
- 23071
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NCBI Accession
- NM_015051, NP_055866
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UniProt
- Q9BS26
Target
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