Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) Peptide
Quick Overview for Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) Peptide (ABIN985803)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBASH3A antibody (Catalog #: ARP45769_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
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Background
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UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It also promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Alias Symbols: CLIP4, STS-2, TULA, TULA-1
Protein Interaction Partner: UBB,ALK,DNM1,UBE2L3
Protein Size: 661 -
Molecular Weight
- 74 kDa
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Gene ID
- 53347
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NCBI Accession
- NM_018961, NP_061834
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UniProt
- P57075
Target
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