Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Middle Region) Peptide
UBE2C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBE2C products
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GTAVGSIRTS STVCLLSGPR ETQDSSKPLV WGLGWDMRLL LELTLQLFLQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2C Antibody(ARP43474_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11,ANAPC2,ENO2,UBE2C,ANAPC2,BUB1B,CDC20,ENO2,MAD2L1,POLM,RNF216,UBASH3B
Protein Size: 161 - Molecular Weight
- 17 kDa
- Gene ID
- 11065
- NCBI Accession
- NM_181799, NP_861515
- UniProt
- O00762
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