Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Middle Region) Peptide
UBE2C
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985808
Quick Overview for Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Middle Region) Peptide (ABIN985808)
Target
UBE2C
(Ubiquitin-Conjugating Enzyme E2C (UBE2C))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GTAVGSIRTS STVCLLSGPR ETQDSSKPLV WGLGWDMRLL LELTLQLFLQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2C Antibody(ARP43474_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11,ANAPC2,ENO2,UBE2C,ANAPC2,BUB1B,CDC20,ENO2,MAD2L1,POLM,RNF216,UBASH3B
Protein Size: 161 -
Molecular Weight
- 17 kDa
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Gene ID
- 11065
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NCBI Accession
- NM_181799, NP_861515
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UniProt
- O00762
Target
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