Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Peptide
UBE2D2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN985810
Quick Overview for Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Peptide (ABIN985810)
Target
UBE2D2
(Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2D2 antibody (Catalog #: ARP43008_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
-
Background
-
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001).[supplied by OMIM].
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: CBL,AMFR,BTRC,CBL,CNOT4,DTX3L,NEDD4,NFKBIA,PJA1,PJA2,RNF11,RNF5,UBE2D2,AMFR,APC11,BARD1,BIRC3,BTRC,CBL,CDKN1B,DDX58,DTX3L,DZIP3,EPS15,FBXL3,FBXO4,FBXO7,FBXW2,ING4,NEDD4,OTUB1,PDZRN3,PJA1,PJA2,POLL,POLM,RAF1,RNF11,RNF2,STAM2,STUB1,TRIM5,UBA6,UBASH3B,UBE3A
Protein Size: 547 -
Molecular Weight
- 60 kDa
-
Gene ID
- 7322
-
NCBI Accession
- NM_018018, NP_003330
-
UniProt
- P62837
Target
-
You are here:
