Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (C-Term) Peptide
UCHL1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN985878
Quick Overview for Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (C-Term) Peptide (ABIN985878)
Target
UCHL1
(Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Sequence
- HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UCHL1 Antibody(ARP58968_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Background
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The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Alias Symbols: PARK5, PGP9.5, PGP95, Uch-L1, PGP 9.5
Protein Interaction Partner: CBX1,CDKN1B,COPS5,HSP90AA1,HSPA8,LAMP2,NEDD8,RANBP9,UBB,UBE2I,CBX1,CCDC14,CDKN1B,COPS5,EGFR,KRT17,KRT4,NEDD8,RANBP9,TP53,UBC,UBE2I,USP21
Protein Size: 223 -
Molecular Weight
- 25 kDa
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Gene ID
- 7345
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NCBI Accession
- NM_004181, NP_004172
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UniProt
- P09936
Target
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