Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide
UCP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985889
Quick Overview for Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide (ABIN985889)
Target
UCP1
(Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GLPAGLQRQI SSASLRIGLY DTVQEFLTAG KETAPSLGSK ILAGLTTGGV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) peptide
UCP1 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (AA 288-303) peptide (Ovalbumin)UCP1 Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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Background
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Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Alias Symbols: SLC25A7, UCP
Protein Interaction Partner: CIDEA,TOMM20,TOMM20
Protein Size: 307 -
Molecular Weight
- 34 kDa
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Gene ID
- 7350
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NCBI Accession
- NM_021833, NP_068605
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UniProt
- P25874
Target
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