UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5) (N-Term) Peptide
Quick Overview for UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5) (N-Term) Peptide (ABIN985904)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- EENFFTLTTY AISWTQDEFD RLLLGHTQSF FETEHLLMKF SRRMAIMNNM
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Characteristics
- UGT1A5,UDP glucuronosyltransferase 1 family, polypeptide A5,UDPGT, UGT1E, UDPGT 1-5, UGT1A5,UDP-glucuronosyltransferase 1-5,UDP-glucuronosyltransferase 1-5,UGT-1E,UGT1*5,OTTHUMP00000065199,UDP-glucuronosyltransferase 1-E,UDP-glucuronosyltransferase 1A5,UDP glycosyltransferase 1 family, polypeptide A5,UDP-glucuronosyltransferase 1 family polypeptide A5s
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UGT1A5 (UDP Glucuronosyltransferase 1 Family, Polypeptide A5 (UGT1A5))
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Background
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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Alias Symbols: UDPGT, UGT1E, UDPGT 1-5
Protein Size: 534 -
Molecular Weight
- 57 kDa
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Gene ID
- 54579
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NCBI Accession
- NM_019078, NP_061951
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UniProt
- P35504
Target
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