Uracil-DNA Glycosylase (UNG) (C-Term) Peptide
UNG
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985938
Quick Overview for Uracil-DNA Glycosylase (UNG) (C-Term) Peptide (ABIN985938)
Target
UNG
(Uracil-DNA Glycosylase (UNG))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UNG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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Target Type
- Viral Protein
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Background
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This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alias Symbols: DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
Protein Interaction Partner: PCNA,PPM1D,PCNA,RPA2,RPA2,UBC
Protein Size: 313 -
Molecular Weight
- 34 kDa
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Gene ID
- 7374
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NCBI Accession
- NM_080911, NP_550433
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UniProt
- P13051
Target
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