Uracil-DNA Glycosylase (UNG) (C-Term) Peptide
-
- Target See all UNG products
- UNG (Uracil-DNA Glycosylase (UNG))
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UNG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- UNG (Uracil-DNA Glycosylase (UNG))
- Target Type
- Viral Protein
- Background
-
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alias Symbols: DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
Protein Interaction Partner: PCNA,PPM1D,PCNA,RPA2,RPA2,UBC
Protein Size: 313 - Molecular Weight
- 34 kDa
- Gene ID
- 7374
- NCBI Accession
- NM_080911, NP_550433
- UniProt
- P13051
-