Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptide
VAMP7
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all VAMP7 products
- VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Vamp7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))
- Background
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Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.
Alias Symbols: Sybl1, TI-VAMP, VAMP-7
Protein Interaction Partner: Stx7
Protein Size: 220 - Molecular Weight
- 25 kDa
- Gene ID
- 20955
- NCBI Accession
- NM_011515, NP_035645
- UniProt
- P70280
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