Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Peptide
VPS4A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986093
Quick Overview for Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Peptide (ABIN986093)
Target
VPS4A
(Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-VPS4A antibody (Catalog #: ARP54916_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
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Background
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VPS4A is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast.The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ22197, SKD1, SKD2, VPS4, VPS4-1, SKD1A
Protein Interaction Partner: CHMP4A,CHMP1A,CHMP1B,CHMP2A,CHMP4A,CHMP4B,CHMP4C,RND2,VPS4A,VPS4B,C19orf62,CHMP1A
Protein Size: 437 -
Molecular Weight
- 49 kDa
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Gene ID
- 27183
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NCBI Accession
- NM_013245, NP_037377
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UniProt
- Q9UN37
Target
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