WW Domain Binding Protein 11 (WBP11) (N-Term) Peptide
Quick Overview for WW Domain Binding Protein 11 (WBP11) (N-Term) Peptide (ABIN986125)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-WBP11 antibody (Catalog #: ARP46241_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- WBP11 (WW Domain Binding Protein 11 (WBP11))
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Background
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WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Alias Symbols: DKFZp779M1063, NPWBP, SIPP1, WBP-11
Protein Interaction Partner: ARF1,C5orf22,CD2BP2,DDX17,GIGYF2,MCRS1,NCF1,NCK2,PIK3R1,PPP1CB,PPP1CC,PQBP1,PRPF40A,RTN4IP1,RUNX1T1,SRC,TRIP10,VIM,ARF1,C5orf22,DDX17,MCRS1,NCK2,PQBP1,RTN4IP1,RUNX1T1,TRIP10
Protein Size: 641 -
Molecular Weight
- 70 kDa
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Gene ID
- 51729
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NCBI Accession
- NM_016312, NP_057396
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UniProt
- Q9Y2W2
Target
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