Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (Middle Region) Peptide
WNT3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986218
Quick Overview for Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (Middle Region) Peptide (ABIN986218)
Target
WNT3
(Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-WNT3 Antibody(ARP49956_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) peptide
WNT3 Reactivity: Human, Mouse, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
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Background
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323
Protein Interaction Partner: FZD1
Protein Size: 355 -
Molecular Weight
- 37 kDa
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Gene ID
- 7473
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NCBI Accession
- NM_030753, NP_110380
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UniProt
- P56703
Target
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