Yes-Associated Protein 1 (YAP1) (C-Term) Peptide
Quick Overview for Yes-Associated Protein 1 (YAP1) (C-Term) Peptide (ABIN986281)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- LNSGTYHSRD ESTDSGLSMS SYSVPRTPDD FLNSVDEMDT GDTINQSTLP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-YAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- YAP1 (Yes-Associated Protein 1 (YAP1))
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Background
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This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: YAP1,YAP65,
Protein Size: 504 -
Molecular Weight
- 54 kDa
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Gene ID
- 10413
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UniProt
- P46937
Target
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