zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (Middle Region) Peptide
ZAP70
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN986320
Quick Overview for zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (Middle Region) Peptide (ABIN986320)
Target
ZAP70
(zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TDKPRPMPMD TSVYESPYSD PEELKDKKLF LKRENLLVAD IELGCGNFGS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Zap70 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
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Background
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Zap70 is a tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Zap70 regulates motility, adhesion and cytokine expression of mature T cells, as well as thymocyte development. Zap70 contributes also to the development and activation of primary B lymphocytes.
Alias Symbols: 70 kDa, AI327364, Srk, TZK, ZAP-70, mrtle, mur
Protein Interaction Partner: Mapk14,Mapk14,Lck
Protein Size: 618 -
Molecular Weight
- 70 kDa
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Gene ID
- 22637
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NCBI Accession
- NM_009539, NP_033565
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UniProt
- P43404
Target
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