Zinc Metalloproteinase, Ste24 (Zmpste24) Peptide
Zmpste24
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986530
$160.46
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100 μg
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United States
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Quick Overview for Zinc Metalloproteinase, Ste24 (Zmpste24) Peptide (ABIN986530)
Target
ZMPSTE24 (Zmpste24)
(Zinc Metalloproteinase, Ste24 (Zmpste24))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZMPSTE24 antibody (Catalog #: ARP46665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
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Background
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ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Size: 475 -
Molecular Weight
- 55 kDa
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Gene ID
- 10269
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NCBI Accession
- NM_005857, NP_005848
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UniProt
- O75844
Target
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