Zinc Finger Protein 259 (znf259) Peptide
znf259
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986701
Quick Overview for Zinc Finger Protein 259 (znf259) Peptide (ABIN986701)
Target
ZNF259 (znf259)
(Zinc Finger Protein 259 (znf259))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZNF259 antibody (Catalog #: ARP38399_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))
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Background
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ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.
Alias Symbols: ZPR1
Protein Interaction Partner: CDK5RAP2,EEF1A1,EGFR,SUMO4,CDK5RAP2,EEF1A1,SNUPN
Protein Size: 459 -
Molecular Weight
- 51 kDa
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Gene ID
- 8882
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NCBI Accession
- NM_003904, NP_003895
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UniProt
- O75312
Target
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