Zinc Finger Protein 446 (ZNF446) Peptide
ZNF446
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986882
$160.46
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100 μg
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Quick Overview for Zinc Finger Protein 446 (ZNF446) Peptide (ABIN986882)
Target
ZNF446
(Zinc Finger Protein 446 (ZNF446))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZNF446 antibody (Catalog #: ARP39319_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ZNF446 (Zinc Finger Protein 446 (ZNF446))
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Background
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ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.
Alias Symbols: ZSCAN30, ZKSCAN20
Protein Interaction Partner: DGCR6L,SUFU,ZNF165,ZNF193,ZNF232,ZNF24,ZNF263,ZNF434,ZNF496,ZSCAN16,DGCR6L,SUFU,ZNF165,ZNF193,ZNF232,ZNF24,ZNF263,ZNF434,ZNF496,ZSCAN16
Protein Size: 450 -
Molecular Weight
- 49 kDa
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Gene ID
- 55663
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NCBI Accession
- NM_017908, NP_060378
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UniProt
- Q9NWS9
Target
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