anti-Pig (Porcine) Mediterranean Fever antibody for Western Blotting

Recommended Mediterranean Fever Antibody (supplied by: Log in to see )

Antigen
Mediterranean Fever (MEFV) Antibodies
  • pyrin
  • MEFV
  • FMF
  • MEF
  • TRIM20
  • rfp domain
  • MEFV, pyrin innate immunity regulator
  • Mediterranean fever
  • MEFV
  • Mefv
Epitope
N-Term
19
18
9
5
5
5
5
1
1
Reactivity
Horse (Equine), Human, Pig (Porcine), Rabbit
65
4
3
3
2
2
2
1
1
1
Host
Rabbit
43
17
5
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
57
42
5
4
4
2
1
1
Options
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Available images

Catalog No. ABIN2780331
$ 289.00
Plus shipping costs $45.00

General

Antigen Mediterranean Fever (MEFV) Antibodies
Epitope N-Term
(19), (18), (9), (5), (5), (5), (5), (1), (1)
Reactivity Horse (Equine), Human, Pig (Porcine), Rabbit
(65), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(43), (17), (5)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (3), (3), (3)
Application Western Blotting (WB)
(57), (42), (5), (4), (4), (2), (1), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN979971
Sequence MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP
Predicted Reactivity Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 77%
Characteristics This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Target Details

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Antigen
Alternative Name MEFV (MEFV Antibody Abstract)
Background MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FMF, MEF, MGC126560, MGC126586, TRIM20
Protein Interaction Partner: COG5, PYCARD, PSTPIP1,
Protein Size: 781
Molecular Weight 86 kDa
Gene ID 4210
NCBI Accession NM_000243, NP_000234
UniProt O15553
Pathways Positive Regulation of Endopeptidase Activity

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 781 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Gattorno, Sormani, DOsualdo, Pelagatti, Caroli, Federici, Cecconi, Solari, Meini, Zulian, Obici, Breda, Martino, Tommasini, Bossi, Govers, Touitou, Woo, Frenkel, Koné-Paut, Baldi, Ceccherini, Martini: "A diagnostic score for molecular analysis of hereditary autoinflammatory syndromes with periodic fever in children." in: Arthritis and rheumatism, Vol. 58, Issue 6, pp. 1823-32, 2008

Images

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Supplier Images
Western Blotting (WB) image for anti-Mediterranean Fever (MEFV) (N-Term) antibody (ABIN2780331) WB Suggested Anti-MEFV Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Pos...
Western Blotting (WB) image for anti-Mediterranean Fever (MEFV) (N-Term) antibody (ABIN2780331) Host: Rabbit Target Name: MEFV Sample Type: Human Fetal Brain Antibody Dilution...