Lactoferrin Protein (full length)
Quick Overview for Lactoferrin Protein (full length) (ABIN1045125)
Target
See all Lactoferrin (LTF) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length
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Purification
- Purified from human milk
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Comment
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Full length native Human lactoferrin
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris pH8.0
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Storage
- -20 °C
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- Lactoferrin (LTF) (Lactotransferrin (LTF))
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Alternative Name
- lactoferrin
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Background
- Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
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Pathways
- Transition Metal Ion Homeostasis
Target
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