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Streptolysin O Protein (SLO) (full length)

This Native Streptolysin O protein is expressed in Bacteria.
Catalog No. ABIN1045131

Quick Overview for Streptolysin O Protein (SLO) (full length) (ABIN1045131)

Target

See all Streptolysin O (SLO) Proteins
Streptolysin O (SLO)

Protein Type

Native

Origin

  • 3
  • 2
  • 2
Streptococcus pyogenes

Source

  • 5
  • 2
Bacteria

Application

ELISA, Western Blotting (WB)

Purity

> 95 % (SDS-PAGE)
  • Protein Characteristics

    full length

    Purification

    Purified from Streptococcus hemolyticus
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  • Comment

    Full length native Streptolysin O

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Repeated freezing and thawing is not recommended.

    Storage

    -20 °C

    Storage Comment

    Aliquot and store at -20 ° C or -80 ° C.
  • Target

    Streptolysin O (SLO)

    Alternative Name

    Streptolysin O

    Background

    Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
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