Streptolysin O Protein (SLO) (full length)
Quick Overview for Streptolysin O Protein (SLO) (full length) (ABIN1045131)
Target
See all Streptolysin O (SLO) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length
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Purification
- Purified from Streptococcus hemolyticus
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Comment
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Full length native Streptolysin O
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Repeated freezing and thawing is not recommended.
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Storage
- -20 °C
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Storage Comment
- Aliquot and store at -20 ° C or -80 ° C.
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- Streptolysin O (SLO)
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Alternative Name
- Streptolysin O
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Background
- Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
Target
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