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Annexin V Protein (AA 2-320)

ANXA5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096018
  • Target See all Annexin V (ANXA5) Proteins
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-320
    Origin
    • 19
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 28
    • 8
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Annexin A5/ANXA5
    Sequence
    MAQVLRGTVT DFPGFDERAD AETLRKAMKG LGTDEESILT LLTSRSNAQR QEISAAFKTL FGRDLLDDLK SELTGKFEKL IVALMKPSRL YDAYELKHAL KGAGTNEKVL TEIIASRTPE ELRAIKQVYE EEYGSSLEDD VVGDTSGYYQ RMLVVLLQAN RDPDAGIDEA QVEQDAQALF QAGELKWGTD EEKFITIFGT RSVSHLRKVF DKYMTISGFQ IEETIDRETS GNLEQLLLAV VKSIRSIPAY LAETLYYAMK GAGTDDHTLI RVMVSRSETD LFNIRKEFRK NFATSLYSMI KGDTSGDYKK ALLLLCGEDD
    Characteristics
    Recombinant Human Annexin A5/ANXA5 is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Asp320) of Human ANXA5.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ANXA5 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, 10 % Glycerol, pH 8.0.
    Preservative
    Dithiothreitol (DTT)
    Precaution of Use
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Alternative Name
    Annexin A5/ANXA5 (ANXA5 Products)
    Background
    Annexin A5 (ANXA5) is a member of the annexin family of calcium-dependent phospholipid binding proteins. ANXA5 is an anticoagulant protein by acting as an indirect inhibitor of the thromboplastin-specific complex. ANXA5 is also a protein kinase C and phospholipase A2 inhibitor. It participate in inflammation, cellular signal transduction, growth and differentiation. ANXA5 binding to phosphatidylserine and sulfatide to regulates coagulability in the blood stream. It also protects sinsuoidal endothelial cells from ischemia reperfusion damage. ANXA5 is important for normal CFTR chloride channel activity.
    Alternative Names: Annexin A5, Anchorin CII, Annexin V, Annexin-5, Calphobindin I, CBP-I, Endonexin II, Lipocortin V, Placental Anticoagulant Protein 4, PP4, Placental Anticoagulant Protein I, PAP-I, Thromboplastin Inhibitor, Vascular Anticoagulant-Alpha, VAC-Alpha, ANXA5,
    Molecular Weight
    35.9 kDa
    UniProt
    P08758
    Pathways
    Apoptosis
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