BCL2A1 Protein (AA 1-152) (His tag)

Catalog No. ABIN1096087

This Recombinant BCL2A1 protein is produced in Escherichia coli (E. coli).

Quick Overview for BCL2A1 Protein (AA 1-152) (His tag) (ABIN1096087)

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-152

Purification tag / Conjugate: This BCL2A1 protein is labelled with His tag.

Purpose: Recombinant Human Bcl-2 Related Protein A1/BCL2A1 (C-6His)

Sequence: MTDCEFGYIY RLAQDYLQCV LQIPQPGSGP SKTSRVLQNV AFSVQKEVEK NLKSCLDNVN VVSVDTARTL FNQVMEKEFE DGIINWGRIV TIFAFEGILI KKLLRQQIAP DVDTYKEISY FVAEFIMNNT GEWIRQNGGW ENGFVKKFEP KSLEHHHHHH

Characteristics: Recombinant Human Bcl-2 Related Protein A1/BCL2A1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser152) of Human BCL2A1.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 10 % Glycerol, pH 7.4.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Alternative Name: Bcl-2 Related Protein A1/BCL2A1

Background: Bcl-2-Related Protein A1 (BCL2A1) is a member of of the BCL-2 protein family which act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. BCL2A1 is a cytoplasm protein and interacts directly with BAK1, BID, BMF and BBC3. BCL2A1 is induced by phorbol ester and inflammatory cytokines, such as TNF or IL1B/interleukin-1 beta, but not by growth factors. BCL2A1 is invovled in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
Alternative Names: Bcl-2-Related Protein A1, Bcl-2-Like Protein 5, Bcl2-L-5, Hemopoietic-Specific Early Response Protein, Protein BFL-1, Protein GRS, BCL2A1, BCL2L5, BFL1, GRS, HBPA1

Molecular Weight: 18.52 kDa

UniProt: Q16548