Defensin beta 4 Protein (DEFB4) (AA 23-72)

Catalog No. ABIN1096119

This Recombinant Defensin beta 4 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Defensin beta 4 Protein (DEFB4) (AA 23-72) (ABIN1096119)

Target: Defensin beta 4 (DEFB4)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 23-72

Purpose: Recombinant Human β-Defensin 4/DEFB4

Sequence: EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP

Characteristics: Recombinant Human beta-Defensin 4/DEFB4 is produced with our E. coli expression system. The target protein is expressed with sequence (Glu23-Pro72) of Human beta-Defensin 4.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Defensin beta 4 (DEFB4)

Alternative Name: beta-defensin-4

Background: Defensins are cationic peptides. It is an important ingredient of the innate immune system. beta-defensins are expressed on some leukocytes and epithelial surfaces. Four human beta-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. beta-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. beta-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, they are released by proteolytic cleavage of a signal sequence.
Alternative Names: Beta-Defensin 104, Beta-Defensin 4, BD-4, DEFB-4, hBD-4, Defensin Beta 104, DEFB104A, DEFB104, DEFB4, DEFB104B

Molecular Weight: 5.99 kDa

UniProt: Q8WTQ1