LI Cadherin Protein (AA 23-787) (His tag)

Catalog No. ABIN1096172

This Recombinant LI Cadherin protein is expressed in Human Cells.

Quick Overview for LI Cadherin Protein (AA 23-787) (His tag) (ABIN1096172)

Target: LI Cadherin

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 23-787

Purification tag / Conjugate: This LI Cadherin protein is labelled with His tag.

Purpose: Recombinant Human Cadherin-17/LI-Cadherin/CDH17 (C-6His)

Sequence: QEGKFSGPLK PMTFSIYEGQ EPSQIIFQFK ANPPAVTFEL TGETDNIFVI EREGLLYYNR ALDRETRSTH NLQVAALDAN GIIVEGPVPI TIEVKDINDN RPTFLQSKYE GSVRQNSRPG KPFLYVNATD LDDPATPNGQ LYYQIVIQLP MINNVMYFQI NNKTGAISLT REGSQELNPA KNPSYNLVIS VKDMGGQSEN SFSDTTSVDI IVTENIWKAP KPVEMVENST DPHPIKITQV RWNDPGAQYS LVDKEKLPRF PFSIDQEGDI YVTQPLDREE KDAYVFYAVA KDEYGKPLSY PLEIHVKVKD INDNPPTCPS PVTVFEVQEN ERLGNSIGTL TAHDRDEENT ANSFLNYRIV EQTPKLPMDG LFLIQTYAGM LQLAKQSLKK QDTPQYNLTI EVSDKDFKTL CFVQINVIDI NDQIPIFEKS DYGNLTLAED TNIGSTILTI QATDADEPFT GSSKILYHII KGDSEGRLGV DTDPHTNTGY VIIKKPLDFE TAAVSNIVFK AENPEPLVFG VKYNASSFAK FTLIVTDVNE APQFSQHVFQ AKVSEDVAIG TKVGNVTAKD PEGLDISYSL RGDTRGWLKI DHVTGEIFSV APLDREAGSP YRVQVVATEV GGSSLSSVSE FHLILMDVND NPPRLAKDYT GLFFCHPLSA PGSLIFEATD DDQHLFRGPH FTFSLGSGSL QNDWEVSKIN GTHARLSTRH TDFEEREYVV LIRINDGGRP PLEGIVSLPV TFCSCVEGSC FRPAGHQTGI PTVGMVDHHH HHH

Characteristics: Recombinant Human Cadherin-17 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln23-Met787) of Human Cadherin-17 fused with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LI Cadherin

Alternative Name: Cadherin-17

Sub Type: Fusionprotein

Background: Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
Alternative Names: Cadherin-17, Intestinal Peptide-Associated Transporter HPT-1, Liver-Intestine Cadherin, LI-Cadherin, CDH17

Molecular Weight: 86 kDa

UniProt: Q12864