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CCL27 Protein

This Recombinant CCL27 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN1096271

Quick Overview for CCL27 Protein (ABIN1096271)

Target

See all CCL27 Proteins
CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Protein Type

Recombinant

Origin

  • 6
  • 4
Human

Source

  • 9
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human C-C Motif Chemokine 27/CCL27

    Sequence

    FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

    Characteristics

    Recombinant Human C-C Motif Chemokine 27/CCL27 produced by E. coli is a single non-glycosylated polypeptide chain containing 88 amino acids with a molecular mass of 10.1 kDa.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl, pH 7.5.

    Handling Advice

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Storage

    4 °C/-20 °C/-80 °C

    Storage Comment

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    3 months
  • Target

    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

    Alternative Name

    CCL27/CTACK

    Background

    Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family, it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form.
    Alternative Names: C-C Motif Chemokine 27, CC Chemokine ILC, Cutaneous T-Cell-Attracting Chemokine, CTACK, Eskine, IL-11 R-Alpha-Locus Chemokine, Skinkine, Small-Inducible Cytokine A27, CCL27, ILC, SCYA27

    Molecular Weight

    10.1 kDa

    UniProt

    Q9Y4X3
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