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CCL27 Protein (AA 25-112)

CCL27 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Catalog No. ABIN6952170
  • Target See all CCL27 Proteins
    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 25-112
    Origin
    • 4
    • 3
    Human
    Source
    • 6
    • 1
    Escherichia coli (E. coli)
    Application
    Cell Migration Assay (CMA)
    Sequence
    FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
    Characteristics
    Recombinant Human CCL27 (CTACK)
    Purity
    > 97 % by SDS PAGE
    Endotoxin Level
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10
    Top Product
    Discover our top product CCL27 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Storage
    -20 °C,-80 °C
    Storage Comment
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Expiry Date
    12 months
  • Target
    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
    Alternative Name
    CCL27 (CTACK) (CCL27 Products)
    Synonyms
    ALP Protein, ILC Protein, CTACK Protein, ESkine Protein, CCL27 Protein, CTAK Protein, ESKINE Protein, PESKY Protein, SCYA27 Protein, AW558992 Protein, Ccl27 Protein, Scya27 Protein, Scya27a Protein, C-C motif chemokine ligand 27 Protein, uncharacterized LOC508933 Protein, chemokine (C-C motif) ligand 27A Protein, Ccl27 Protein, CCL27 Protein, LOC508933 Protein, Ccl27a Protein
    Background
    Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.
    Molecular Weight
    10.149kDa
    UniProt
    Q9Y4X3
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