FAM3C Protein (AA 25-227) (His tag)

Catalog No. ABIN1096618

Recombinant FAM3C protein expressed in Human Cells.

Quick Overview for FAM3C Protein (AA 25-227) (His tag) (ABIN1096618)

Target: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 25-227

Purification tag / Conjugate: This FAM3C protein is labelled with His tag.

Purpose: Recombinant Human Protein FAM3C (C-6His)

Sequence: QVFEIKMDAS LGNLFARSAL DTAARSTKPP RYKCGISKAC PEKHFAFKMA SGAANVVGPK ICLEDNVLMS GVKNNVGRGI NVALANGKTG EVLDTKYFDM WGGDVAPFIE FLKAIQDGTI VLMGTYDDGA TKLNDEARRL IADLGSTSIT NLGFRDNWVF CGGKGIKTKS PFEQHIKNNK DTNKYEGWPE VVEMEGCIPQ KQDVDHHHHH H

Characteristics: Recombinant Human Protein FAM3C is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Q25-D227) of Human FAM3C fused with a polyhistidine tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Alternative Name: fam3c

Sub Type: Fusionprotein

Background: FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.
Alternative Names: Protein FAM3C, Interleukin-Like EMT Inducer, FAM3C, ILEI

Molecular Weight: 23.2 kDa

UniProt: Q92520