Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 22-152) protein (His tag)

Details for Product No. ABIN1097053
Protein Name
  • CD306
  • leukocyte associated immunoglobulin like receptor 2
  • LAIR2
Protein Characteristics
AA 22-152
4
4
1
1
Origin
Human
15
Source
Human Cells
5
4
4
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This LAIR2 protein is labelled with His tag.
Application
Functional Studies (Func)
Options
Purpose Recombinant Human LAIR-2/CD306 (C-6His)
Sequence QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA PVDHHHHHH
Characteristics Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2/LAIR2 produced by transfected human cells is a secreted protein with sequence (Gln22-Pro152) of Human LAIR2 fused with a polyhistidine tag at the C-terminus.
Purity > 95 % as determined by reducing SDS-PAGE.
Sterility 0.2 μm filtered
Endotoxin Level Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Protein Name
Sub Type Fusionprotein
Background Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
Alternative Names: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2
Molecular Weight 15.1 kDa
UniProt Q6ISS4
Restrictions For Research Use only
Format Lyophilized
Reconstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Handling Advice Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Storage 4 °C/-20 °C/-80 °C
Storage Comment Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Expiry Date 3 months
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