LAIR2 Protein (Fc Tag)
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- Target See all LAIR2 Proteins
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This LAIR2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human Leukocyte-associated Immunoglobulin-like Receptor 2/ LAIR2/CD306 (C-Fc)
- Sequence
- Gln22-Pro152
- Characteristics
- Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gln22-Pro152 is expressed with a Fc tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LAIR2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Alternative Name
- Leukocyte-associated Immunoglobulin-like Receptor 2/ LAIR2/CD306 (LAIR2 Products)
- Synonyms
- CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
- Background
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Background: Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83 % amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
Synonym: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2
- Molecular Weight
- 41 kDa
- UniProt
- Q6ISS4
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