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LAIR2 Protein (AA 22-152) (His tag)

LAIR2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505579
  • Target See all LAIR2 Proteins
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-152
    Origin
    Human
    Source
    • 8
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LAIR2 protein is labelled with His tag.
    Sequence
    Gln22-Pro152
    Characteristics
    Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gln22-Pro152 is expressed with a 6His tag at the C-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product LAIR2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Alternative Name
    LAIR2 (LAIR2 Products)
    Synonyms
    CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
    Background

    Background: Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83 % amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.

    Synonym: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2

    Molecular Weight
    15.1 kDa
    UniProt
    Q6ISS4
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