CSH1 Protein (AA 27-217) (His tag)
Quick Overview for CSH1 Protein (AA 27-217) (His tag) (ABIN1097349)
Target
See all CSH1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 27-217
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Purification tag / Conjugate
- This CSH1 protein is labelled with His tag.
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Purpose
- Recombinant Human Placental Lactogen/CSH1 (C-6His)
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Sequence
- VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG FVDHHHHHH
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Characteristics
- Recombinant Human Chorionic Somatomammotropin Hormone/CSH1 produced by transfected human cells is a secreted protein with sequence (Val27-Phe217) of Human CSH1 fused with a polyhistidine tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (AA 1-217) protein (GST tag)
CSH1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (AA 27-217) (Active) protein (His tag)CSH1 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (AA 27-217) protein (His tag)CSH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CSH1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Storage
- 4 °C/-20 °C/-80 °C
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Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
Expiry Date
- 3 months
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- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
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Alternative Name
- placental-lactogen
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Sub Type
- Fusionprotein
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Background
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Chorionic Somatomammotropin Hormone (CSH1) belongs to the Somatotropin/Prolactin family. It is located at the growth hormone locus on chromosome 17. It is produced by cells in the syncytiotrophoblast layer of the placenta only during pregnancy. Although CSH1 does not interact with GHR but only activates PRLR through zinc-induced dimerization. It is expressed mainly in the placenta and utilizes multiple transcription initiation sites. CSH1 plays an important role in stimulating lactation, growth control and metabolism.
Alternative Names: Chorionic Somatomammotropin Hormone, Choriomammotropin, Lactogen, Placental Lactogen, PL, CSH1, CSH2 -
Molecular Weight
- 23.35 kDa
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UniProt
- P01243
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Pathways
- Response to Growth Hormone Stimulus
Target
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