SERPINB6 Protein (AA 1-376) (His tag,TRX tag)

Catalog No. ABIN1097520

This Recombinant SERPINB6 protein is expressed in Escherichia coli (E. coli).

Quick Overview for SERPINB6 Protein (AA 1-376) (His tag,TRX tag) (ABIN1097520)

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-376

Purification tag / Conjugate: This SERPINB6 protein is labelled with His tag,TRX tag.

Purpose: Recombinant Human Serpin B6/Placental Thrombin Inhibitor (N-Trx, 6His)

Sequence: MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ADIGSEFHMD VLAEANGTFA LNLLKTLGKD NSKNVFFSPM SMSCALAMVY MGAKGNTAAQ MAQILSFNKS GGGGDIHQGF QSLLTEVNKT GTQYLLRVAN RLFGEKSCDF LSSFRDSCQK FYQAEMEELD FISAVEKSRK HINTWVAEKT EGKIAELLSP GSVDPLTRLV LVNAVYFRGN WDEQFDKENT EERLFKVSKN EEKPVQMMFK QSTFKKTYIG EIFTQILVLP YVGKELNMII MLPDETTDLR TVEKELTYEK FVEWTRLDMM DEEEVEVSLP RFKLEESYDM ESVLRNLGMT DAFELGKADF SGMSQTDLSL SKVVHKSFVE VNEEGTEAAA ATAAIMMMRC ARFVPRFCAD HPFLFFIQHS KTNGILFCGR FSSP

Characteristics: Recombinant Human Serpin B6 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Pro376) of Human SERPINB6 fused with a TraxA, His tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Alternative Name: Serpin-B6

Sub Type: Fusionprotein

Background: Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Alternative Names: Serpin B6, Cytoplasmic Antiproteinase, CAP, Peptidase Inhibitor 6, PI-6, Placental Thrombin Inhibitor, SERPINB6, PI6, PTI

Molecular Weight: 60.7 kDa

UniProt: P35237