OAZ1 Protein (AA 1-228) (His tag)

Catalog No. ABIN1098382

Recombinant OAZ1 protein expressed in Escherichia coli (E. coli).

Quick Overview for OAZ1 Protein (AA 1-228) (His tag) (ABIN1098382)

Target: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 85 %

Product Details

Protein Characteristics: AA 1-228

Purification tag / Conjugate: This OAZ1 protein is labelled with His tag.

Sequence: MVKSSLQ RILNSHCFAR EKEGDKPSAT IHASRTMPLL SLHSRGGSSS ESSRVSLHCC SNPGPGPRWC SDAPHPPLKI PGGRGNSQRD HNLSANLFYS DDRLNVTEEL TSNDKTRILN VQSRLTDAKR INWRTVLSGG SLYIEIPGGA LPEGSKDSFA VLLEFAEEQL RADHVFICFH KNREDRAALL RTFSFLGFEI VRPGHPLVPK RPDACFMAYT FERESSGEEE E

Purification: > 85% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol,1 mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Alternative Name: OAZ1

Background: Ornithine decarboxylase antizyme 1, also known as OAZ1, belongs to the ODC antizyme family. It expression is auto-regulated by polyamine-enhanced translational frameshifting. OAZ1 negatively regulates polyamine synthesis by enhancing the negative feedback loop controlling ornithine decarboxylase (ODC) activity. The OAZ1 encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation. Recombinant human OAZ1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 27.8 kDa (251aa) confirmed by MALDI-TOF

NCBI Accession: NP_004143