HMGCR Protein (AA 1-835) (GST tag)
Quick Overview for HMGCR Protein (AA 1-835) (GST tag) (ABIN1306814)
Target
See all HMGCR ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-835
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Purification tag / Conjugate
- This HMGCR protein is labelled with GST tag.
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Purpose
- HMGCR (Human) Recombinant Protein (P01)
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Sequence
- MLSRLFRMHG LFVASHPWEV IVGTVTLTIC MMSMNMFTGN NKICGWNYEC PKFEEDVLSS DIIILTITRC IAILYIYFQF QNLRQLGSKY ILGIAGLFTI FSSFVFSTVV IHFLDKELTG LNEALPFFLL LIDLSRASTL AKFALSSNSQ DEVRENIARG MAILGPTFTL DALVECLVIG VGTMSGVRQL EIMCCFGCMS VLANYFVFMT FFPACVSLVL ELSRESREGR PIWQLSHFAR VLEEEENKPN PVTQRVKMIM SLGLVLVHAH SRWIADPSPQ NSTADTSKVS LGLDENVSKR IEPSVSLWQF YLSKMISMDI EQVITLSLAL LLAVKYIFFE QTETESTLSL KNPITSPVVT QKKVPDNCCR REPMLVRNNQ KCDSVEEETG INRERKVEVI KPLVAETDTP NRATFVVGNS SLLDTSSVLV TQEPEIELPR EPRPNEECLQ ILGNAEKGAK FLSDAEIIQL VNAKHIPAYK LETLMETHER GVSIRRQLLS KKLSEPSSLQ YLPYRDYNYS LLGGGASSRV LADGMTRGPV VRLPRACDSA EVKAWLETSE GFAVIKEAFD STSRFARLQK LHTSIAGRNL YIRFQSRSGD AMGMNMISKG TEKALSKLHE YFPEMQILAV SGNYCTDKKP AAINWIEGRG KSVVCEAVIP AKVVREVLKT TTEAMIEVNI NKNLVGSAMA GSIGGYNAHA ANIVTAIYIA CGQDAAQNVG SSNCITLMEA SGPTNEDLYI SCTMPSIEIG TVGGGTNLLP QQACLQMLGV QGACKDNPGE NARQLARIVC GTVMAGELSL MAALAAGHLV KSHMIHNRSK INLQDLQGAC TKKTA
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Characteristics
- Human HMGCR full-length ORF ( AAH33692.1, 1 a.a. - 835 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-887) protein (His tag)
custom-made HMGCR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-888) protein (His tag)custom-made HMGCR Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 700-860) protein (His tag)HMGCR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 588-887), (partial) protein (His tag)HMGCR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
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Alternative Name
- HMGCR
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Background
- Gene: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
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Gene ID
- 3156
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Pathways
- AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
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